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DOI: Navazesh M, Kumar SKS

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Among such species the radical forms are removed via non-enzymatic reduction with GSH, whereas the elimination of hydroperoxides requires enzymatic catalysis by GPX and catalase

Glutamine and its oncometabolites The discovery of R-2-hydroxyglutarate (R-2-HG) accumulation in several tumors encouraged investigators to initially establish the term oncometabolite 111

Mechanism understanding helps troubleshooting non-responders, switching to peptides targeting different pathways potentially more relevant for specific individual pathophysiology